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Document type:
Journal Article 
Author(s):
Cirac, Ana; Stützle, Simon; Dieckmeyer, Michael; Adhikary, Dinesh; Moosmann, Andreas; Körber, Nina; Bauer, Tanja; Witter, Klaus; Delecluse, Henri-Jacques; Behrends, Uta; Mautner, Josef 
Title:
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity. 
Abstract:
The Epstein-Barr virus (EBV) establishes lifelong infections in > 90% of the human population. Although contained as asymptomatic infection by the immune system in most individuals, EBV is associated with the pathogenesis of approximately 1.5% of all cancers in humans. Some of these EBV-associated tumors have been successfully treated by the infusion of virus-specific T-cell lines. Recent sequence analyses of a large number of viral isolates suggested that distinct EBV strains have evolved in di...    »
 
Journal title abbreviation:
Cancer Immunol Immunother 
Year:
2018 
Journal volume:
67 
Journal issue:
Pages contribution:
663-674 
Print-ISSN:
0340-7004 
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin