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Title:

Induction of IL-10-balanced immune profiles following exposure to LTA from Staphylococcus epidermidis.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Volz, Thomas; Kaesler, Susanne; Draing, Christian; Hartung, Thomas; Röcken, Martin; Skabytska, Yuliya; Biedermann, Tilo
Abstract:
Staphylococcus epidermidis colonises human skin without apparent inflammation, but a dominance of S. epidermidis and S. aureus is characteristic of cutaneous microbial dysbiosis in atopic dermatitis (AD). While S. aureus can trigger AD, the role of S. epidermidis is less understood. We characterised consequences of innate immune sensing of lipoteichoic acid (LTA) preparations derived from S. epidermidis (epi-LTA) or S. aureus (aureus-LTA). Therefore, dendritic cell (DC) activation and consecutiv...     »
Journal title abbreviation:
Exp Dermatol
Year:
2018
Journal volume:
27
Journal issue:
4
Pages contribution:
318-326
Fulltext / DOI:
doi:10.1111/exd.13540
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29569765
Print-ISSN:
0906-6705
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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