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Title:

Effect of Erythropoietin in patients with acute myocardial infarction: five-year results of the REVIVAL-3 trial.

Document type:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Article
Author(s):
Steppich, Birgit; Groha, Philip; Ibrahim, Tareq; Schunkert, Heribert; Laugwitz, Karl-Ludwig; Hadamitzky, Martin; Kastrati, Adnan; Ott, Ilka
Abstract:
Erythropoietin (EPO) has been suggested to promote cardiac repair after MI. However, the randomized, double-blind, placebo controlled REVIVAL-3 trial showed that short term high dose EPO in timely reperfused myocardium does not improve left ventricular ejection fraction after 6 months. Moreover, the study raised safety concerns due to a trend towards a higher incidence of adverse clinical events as well as a increase in neointima formation after treatment with EPO. The present study therefore ai...     »
Journal title abbreviation:
BMC Cardiovasc Disord
Year:
2017
Journal volume:
17
Journal issue:
1
Pages contribution:
38
Language:
eng
Fulltext / DOI:
doi:10.1186/s12872-016-0464-3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28109258
Print-ISSN:
1471-2261
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Radiologie; Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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