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Titel:

Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.

Dokumenttyp:
Journal Article; Article
Autor(en):
Geng, Xiaocong; Liu, Yueyang; Diersch, Sandra; Kotzsch, Matthias; Grill, Sabine; Weichert, Wilko; Kiechle, Marion; Magdolen, Viktor; Dorn, Julia
Abstract:
KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognosis. In the present study, we selected a homogeneous cohort including 139 patients of advanced high-grade serous ovarian cancer (FIGO stage III/IV) and assessed the mRNA levels of KLK9, 10, 11, and 15 in tumor tissue by quantitative PCR. No significant associations of KLK9, 10, 11, and 15 mRNA with established clinical parameters (residual tumor mass, ascitic fluid volume) were found. Pronounced co...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2017
Band / Volume:
12
Heft / Issue:
11
Seitenangaben Beitrag:
e0186847
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0186847
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29095848
Print-ISSN:
1932-6203
TUM Einrichtung:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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