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Title:

Genetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue Attenuation

Document type:
Article
Author(s):
Massner, Christoph; Sigmund, Felix; Pettinger, Susanne; Seeger, Markus; Hartmann, Carolin; Ivleva, Natalia P.; Niessner, Reinhard; Fuchs, Helmut; de Angelis, Martin Hrabe; Stelzl, Anja; Koonakampully, Neha Lal; Rolbieski, Hannes; Wiedwald, Ulf; Spasova, Marina; Wurst, Wolfgang; Ntziachristos, Vasilis; Winklhofer, Michael; Westmeyer, Gil G.
Abstract:
Nanomaterials are of enormous value for biomedical applications because of their customizable features. However, the material properties of nanomaterials can be altered substantially by interactions with tissue thus making it important to assess them in the specific biological context to understand and tailor their effects. Here, a genetically controlled system is optimized for cellular uptake of superparamagnetic ferritin and subsequent trafficking to lysosomes. High local concentrations of pho...     »
Journal title abbreviation:
Adv. Funct. Mater.
Year:
2018
Journal volume:
28
Journal issue:
19
Fulltext / DOI:
doi:10.1002/adfm.201706793
Print-ISSN:
1616-301X
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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