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Title:

Dual-Modality Surface-Enhanced Resonance Raman Scattering and Multispectral Optoacoustic Tomography Nanoparticle Approach for Brain Tumor Delineation.

Document type:
Article
Author(s):
Neuschmelting, Volker; Harmsen, Stefan; Beziere, Nicolas; Lockau, Hannah; Hsu, Hsiao-Ting; Huang, Ruimin; Razansky, Daniel; Ntziachristos, Vasilis; Kircher, Moritz F.
Abstract:
Difficulty in visualizing glioma margins intraoperatively remains a major issue in the achievement of gross total tumor resection and, thus, better clinical outcome of glioblastoma (GBM) patients. Here, the potential of a new combined optical + optoacoustic imaging method for intraoperative brain tumor delineation is investigated. A strategy using a newly developed gold nanostar synthesis method, Raman reporter chemistry, and silication method to produce dual-modality contrast agents for combine...     »
Journal title abbreviation:
Small
Year:
2018
Journal volume:
14
Journal issue:
23
Fulltext / DOI:
doi:10.1002/smll.201800740
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29726109
Print-ISSN:
1613-6810
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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