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Titel:

Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.

Dokumenttyp:
Article
Autor(en):
Fuenzalida-Werner, Juan Pablo; Janowski, Robert; Mishra, Kanuj; Weidenfeld, Ina; Niessing, Dierk; Ntziachristos, Vasilis; Stiel, Andre C.
Abstract:
Small, ultra-red fluorescence protein (smURFP) introduces the non-native biliverdin (BV) chromophore to phycobiliproteins (PBPs), allowing them to be used as transgenic labels for in vivo mammalian imaging. Presently, no structural information exists for PBPs bound to the non-native BV chromophore, which limits the further development of smURFP and related proteins as imaging labels or indicators. Here we describe the first crystal structure of a PBP bound to BV. The structures of smURFP-Y56R wi...     »
Zeitschriftentitel:
J Struct Biol
Jahr:
2018
Band / Volume:
204
Heft / Issue:
3
Seitenangaben Beitrag:
519-522
Volltext / DOI:
doi:10.1016/j.jsb.2018.09.013
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30287387
Print-ISSN:
1047-8477
TUM Einrichtung:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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