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Title:

Sonophore labeled RGD: a targeted contrast agent for optoacoustic imaging.

Document type:
Journal Article; Article
Author(s):
Haedicke, Katja; Brand, Christian; Omar, Murad; Ntziachristos, Vasilis; Reiner, Thomas; Grimm, Jan
Abstract:
Optoacoustic imaging is a rapidly expanding field for the diagnosis, characterization, and treatment evaluation of cancer. However, the availability of tumor specific exogenous contrast agents is still limited. Here, we report on a small targeted contrast agent for optoacoustic imaging using a black hole quencher (BHQ) dye. The sonophore BHQ-1 exhibited strong, concentration-dependent, optoacoustic signals in phantoms, demonstrating its ideal suitability for optoacoustic imaging. After labeling...     »
Journal title abbreviation:
Photoacoustics
Year:
2017
Journal volume:
6
Pages contribution:
1-8
Language:
eng
Fulltext / DOI:
doi:10.1016/j.pacs.2017.03.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28393018
Print-ISSN:
2213-5979
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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