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Title:

Mitochondria in non-alcoholic fatty liver disease.

Document type:
Journal Article
Author(s):
Simões, Inês C M; Fontes, Adriana; Pinton, Paolo; Zischka, Hans; Wieckowski, Mariusz R
Abstract:
NAFLD is a common disease in Western society and ranges from steatosis to steatohepatitis and to end-stage liver disease. The molecular mechanisms that cause the progression of steatosis to severe liver damage are not fully understood. One suggested mechanism involves the oxidation of biomolecules by mitochondrial ROS which initiates a vicious cycle of exacerbated mitochondrial dysfunction and increased hepatocellular oxidative damage. This may ultimately pave the way for hepatic inflammation an...     »
Journal title abbreviation:
Int J Biochem Cell Biol
Year:
2018
Journal volume:
95
Pages contribution:
93-99
Language:
eng
Fulltext / DOI:
doi:10.1016/j.biocel.2017.12.019
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29288054
Print-ISSN:
1357-2725
TUM Institution:
Institut für Toxikologie und Umwelthygiene
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