User: Guest  Login
Title:

Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.

Document type:
Journal Article
Author(s):
Dettmar, Larissa; Ahmed, Nancy; Kotzsch, Matthias; Diersch, Sandra; Napieralski, Rudolf; Darmoul, Dalila; Schmitt, Manfred; Weichert, Wilko; Kiechle, Marion; Dorn, Julia; Magdolen, Viktor
Abstract:
Gene expression of a variety of the 15 members of the KLK serine protease family is dysregulated in ovarian cancer. We aimed at determining the clinical relevance of KLK13 and KLK14 mRNA expression in tumor tissues of a homogeneous patient cohort afflicted with advanced high-grade serous ovarian cancer (FIGO stage III/IV).mRNA expression levels of KLK13 and KLK14 were assessed by quantitative PCR in tumor tissue of 91 patients and related with clinical factors and patients' outcome.There was no...     »
Journal title abbreviation:
J Cancer Res Clin Oncol
Year:
2018
Journal volume:
144
Journal issue:
6
Pages contribution:
1109-1118
Language:
eng
Fulltext / DOI:
doi:10.1007/s00432-018-2623-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29546479
Print-ISSN:
0171-5216
TUM Institution:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
 BibTeX