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Titel:

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations.

Dokumenttyp:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Lamina, Claudia; Friedel, Salome; Coassin, Stefan; Rueedi, Rico; Yousri, Noha A; Seppälä, Ilkka; Gieger, Christian; Schönherr, Sebastian; Forer, Lukas; Erhart, Gertraud; Kollerits, Barbara; Marques-Vidal, Pedro; Ried, Janina; Waeber, Gerard; Bergmann, Sven; Dähnhardt, Doreen; Stöckl, Andrea; Kiechl, Stefan; Raitakari, Olli T; Kähönen, Mika; Willeit, Johann; Kedenko, Ludmilla; Paulweber, Bernhard; Peters, Annette; Meitinger, Thomas; Strauch, Konstantin; Lehtimäki, Terho; Hunt, Steven C; Vollenwei...     »
Abstract:
Apolipoprotein A-IV (apoA-IV) is a major component of HDL and chylomicron particles and is involved in reverse cholesterol transport. It is an early marker of impaired renal function. We aimed to identify genetic loci associated with apoA-IV concentrations and to investigate relationships with known susceptibility loci for kidney function and lipids. A genome-wide association meta-analysis on apoA-IV concentrations was conducted in five population-based cohorts (n = 13,813) followed by two addit...     »
Zeitschriftentitel:
Hum Mol Genet
Jahr:
2016
Band / Volume:
25
Heft / Issue:
16
Seitenangaben Beitrag:
3635-3646
Sprache:
eng
Volltext / DOI:
doi:10.1093/hmg/ddw211
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27412012
Print-ISSN:
0964-6906
TUM Einrichtung:
Institut für Humangenetik
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