Benutzer: Gast  Login
Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't 
Autor(en):
Honrath, Birgit; Matschke, Lina; Meyer, Tammo; Magerhans, Lena; Perocchi, Fabiana; Ganjam, Goutham K; Zischka, Hans; Krasel, Cornelius; Gerding, Albert; Bakker, Barbara M; Bünemann, Moritz; Strack, Stefan; Decher, Niels; Culmsee, Carsten; Dolga, Amalia M 
Titel:
SK2 channels regulate mitochondrial respiration and mitochondrial Ca uptake. 
Abstract:
Mitochondrial calcium ([Ca]) overload and changes in mitochondrial metabolism are key players in neuronal death. Small conductance calcium-activated potassium (SK) channels provide protection in different paradigms of neuronal cell death. Recently, SK channels were identified at the inner mitochondrial membrane, however, their particular role in the observed neuroprotection remains unclear. Here, we show a potential neuroprotective mechanism that involves attenuation of [Ca] uptake upon SK chann...    »
 
Zeitschriftentitel:
Cell Death Differ 
Jahr:
2017 
Band / Volume:
24 
Heft / Issue:
Seitenangaben Beitrag:
761-773 
Sprache:
eng 
Volltext / DOI:
Print-ISSN:
1350-9047 
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene