User: Guest  Login
Title:

Mucin Coatings Prevent Tissue Damage at the Cornea-Contact Lens Interface

Document type:
Zeitschriftenaufsatz
Author(s):
Winkeljann, Benjamin; Boettcher, Kathrin; Balzer, Bizan N.; Lieleg, Oliver
Abstract:
With a prevalence of more than 10%, keratoconjunctivitis sicca (commonly known as dry eye syndrome) is one of the most frequent forms of ocular diseases; among contact lens wearers, this condition occurs even more often. Key components of the protective tear film are mucins, large glycoproteins that serve as molecular lubricants on many epithelial body surfaces. It is likely that, in the absence of a proper mucinous lubrication layer on the cornea surface, increased friction and tissue damage i...     »
Keywords:
cornea; dry eye; lubrication; surface modification; tribology; ATOMIC-FORCE MICROSCOPY; FRICTION COEFFICIENT MEASUREMENT; OCULAR SURFACE; ARTICULAR-CARTILAGE; TAPPING-MODE; TRACT MUCINS; TEAR FILM; WEAR; LUBRICATION; XEROSTOMIA
Dewey Decimal Classification:
500 Naturwissenschaften
Journal title:
Advanced Materials Interfaces
Year:
2017
Journal volume:
4
Journal issue:
19
Pages contribution:
1700186
Covered by:
Scopus
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1002/admi.201700186
WWW:
http://onlinelibrary.wiley.com/doi/10.1002/admi.201700186/full
Publisher:
Wiley-Blackwell
E-ISSN:
2196-7350
Date of publication:
25.07.2017
TUM Institution:
Fachgebiet für Biomechanik, MW
Format:
Bild/Text
 BibTeX