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Titel:

Application of theoretical methods to increase succinate production in engineered strains

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
M. A. Valderrama-Gomez; D. Kreitmayer; S. Wolf; A. Marin-Sanguino; A. Kremling
Abstract:
Computational methods have enabled the discovery of non-intuitive strategies to enhance the production of a variety of target molecules. In the case of succinate production, reviews covering the topic have not yet analyzed the impact and future potential that such methods may have. In this work, we review the application of computational methods to the production of succinic acid. We found that while a total of 26 theoretical studies were published between 2002 and 2016, only 10 studies reported...     »
Stichworte:
Succinic acid; Metabolic engineering; Systems biotechnology
Zeitschriftentitel:
Bioprocess and Biosystems Engineering
Jahr:
2017
Volltext / DOI:
doi:10.1007/s00449-016-1729-z
WWW:
https://link.springer.com/article/10.1007/s00449-016-1729-z
TUM Einrichtung:
Professur für Systembiotechnologie
Eingabe:
29.03.2017
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