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Titel:

The Hippo signal transduction network for exercise physiologists.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Gabriel BM, Hamilton DL, Tremblay AM, Wackerhage H
Abstract:
The ubiquitous transcriptional coactivators Yap (gene symbol Yap1) and Taz (gene symbol Wwtr1) regulate gene expression mainly by coactivating the Tead transcription factors. Being at the center of the Hippo signaling network, Yap and Taz are regulated by the Hippo kinase cassette and additionally by a plethora of exercise-associated signals and signaling modules. These include mechanotransduction, the AKT-mTORC1 network, the SMAD transcription factors, hypoxia, glucose homeostasis, AMPK,...     »
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
J Appl Physiol
Jahr:
2016
Band / Volume:
120
Jahr / Monat:
2016-05
Heft / Issue:
10
Seitenangaben Beitrag:
1105-17
Volltext / DOI:
doi:10.1152/japplphysiol.01076.2015
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26940657
Impact Factor:
3.004
Semester:
SS 16
TUM Einrichtung:
Sportbiologie
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