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Titel:

Progressive multifocal leukoencephalopathy after fingolimod treatment.

Dokumenttyp:
Article; Journal Article
Autor(en):
Berger, Joseph R; Cree, Bruce A; Greenberg, Benjamin; Hemmer, Bernhard; Ward, Brian J; Dong, Victor M; Merschhemke, Martin
Abstract:
OBJECTIVE: We describe the characteristics of the 15 patients with fingolimod-associated progressive multifocal leukoencephalopathy (PML) identified from the Novartis data safety base and provide risk estimates for the disorder. METHODS: The Novartis safety database was searched for PML cases with a data lock point of August 31, 2017. PML classification was based on previously published criteria. The risk and incidence were estimated using the 15 patients with confirmed PML and the overall popul...     »
Zeitschriftentitel:
Neurology
Jahr:
2018
Band / Volume:
90
Heft / Issue:
20
Seitenangaben Beitrag:
e1815-e1821
Volltext / DOI:
doi:10.1212/WNL.0000000000005529
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29669908
Print-ISSN:
0028-3878
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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