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Titel:

T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target.

Dokumenttyp:
Journal Article
Autor(en):
Mayer, Kristine E; Mall, Sabine; Yusufi, Nahid; Gosmann, Dario; Steiger, Katja; Russelli, Lisa; Bianchi, Henrique de Oliviera; Audehm, Stefan; Wagner, Ricarda; Bräunlein, Eva; Stelzl, Anja; Bassermann, Florian; Weichert, Wilko; Weber, Wolfgang; Schwaiger, Markus; D'Alessandria, Calogero; Krackhardt, Angela M
Abstract:
Cancer immunotherapy has proven high efficacy in treating diverse cancer entities by immune checkpoint modulation and adoptive T-cell transfer. However, patterns of treatment response differ substantially from conventional therapies, and reliable surrogate markers are missing for early detection of responders versus non-responders. Current imaging techniques using F-fluorodeoxyglucose-positron-emmission-tomograpy (F-FDG-PET) cannot discriminate, at early treatment times, between tumor progressio...     »
Zeitschriftentitel:
Theranostics
Jahr:
2018
Band / Volume:
8
Heft / Issue:
21
Seitenangaben Beitrag:
6070-6087
Sprache:
eng
Volltext / DOI:
doi:10.7150/thno.27275
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30613283
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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