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Titel:

Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.

Dokumenttyp:
Journal Article
Autor(en):
Geng, Xiaocong; Liu, Yueyang; Dreyer, Tobias; Bronger, Holger; Drecoll, Enken; Magdolen, Viktor; Dorn, Julia
Abstract:
Several members of the KLK family have been proposed to modulate various tumor-relevant processes. Previously, we have shown that in advanced high-grade serous ovarian cancer tissue high KLK11 mRNA levels were significantly associated with prolonged overall and progression-free patients' survival. Furthermore, KLK11 mRNA expression positively correlated with KLK10 mRNA. In the present study, we examined the prognostic value for both KLK10 and KLK11 on the protein expression level by immunohistoc...     »
Zeitschriftentitel:
Am J Cancer Res
Jahr:
2018
Band / Volume:
8
Heft / Issue:
9
Seitenangaben Beitrag:
1856-1864
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30323977
TUM Einrichtung:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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