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Title:

Diurnal rhythmicity of infant fecal microbiota and metabolites: A randomized controlled interventional trial with infant formula

Document type:
Zeitschriftenaufsatz
Author(s):
Heppner, Nina; Reitmeier, Sandra; Heddes, Marjolein; Merino, Michael Vig; Schwartz, Leon; Dietrich, Alexander; List, Markus; Gigl, Michael; Meng, Chen; van der Veen, Daan R.; Schirmer, Melanie; Kleigrewe, Karin; Omer, Hélène; Kiessling, Silke; Haller, Dirk
Abstract:
Microbiota assembly in the infant gut is influenced by diet. Breastfeeding and human breastmilk oligosaccharides promote the colonization of beneficial bifidobacteria. Infant formulas are supplemented with bifidobacteria or complex oligosaccharides, notably galacto-oligosaccharides (GOS), to mimic breast milk. To compare microbiota development across feeding modes, this randomized controlled intervention study (German Clinical Trial DRKS00012313) longitudinally sampled infant stool during the fi...     »
Keywords:
BayBioMS; 16S sequencing; Bifidobacteria; GOS; breastfeeding; circadian rhythm; formula; infant; metabolomics; microbiota; shot gun.
Journal title:
Cell Host & Microbe
Year:
2024
Fulltext / DOI:
doi:10.1016/j.chom.2024.02.015
Publisher:
Elsevier BV
E-ISSN:
1931-3128
Date of publication:
01.04.2024
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