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Title:

A 14-Day Double-Blind, Randomized, Controlled Crossover Intervention Study with Anti-Bacterial Benzyl Isothiocyanate from Nasturtium (Tropaeolum majus) on Human Gut Microbiome and Host Defense

Document type:
Zeitschriftenaufsatz
Author(s):
Pfäffle, Simon P.; Herz, Corinna; Brombacher, Eva; Proietti, Michele; Gigl, Michael; Hofstetter, Christoph K.; Mittermeier-Kleßinger, Verena K.; Claßen, Sophie; Tran, Hoai T. T.; Dawid, Corinna; Kreutz, Clemens; Günther, Stefan; Lamy, Evelyn
Abstract:
Despite substantial heterogeneity of studies, there is evidence that antibiotics commonly used in primary care influence the composition of the gastrointestinal microbiota in terms of changing their composition and/or diversity. Benzyl isothiocyanate (BITC) from the food and medicinal plant nasturtium (Tropaeolum majus) is known for its antimicrobial activity and is used for the treatment of infections of the draining urinary tract and upper respiratory tract. Against this background, we raised...     »
Keywords:
BayBioMS; BITC; Escherichia coli; antimicrobial; gut microbiome; human beta defensin 1; metabolome; nasturtium
Journal title:
Nutrients
Year:
2024
Journal volume:
16
Journal issue:
3
Pages contribution:
373
Fulltext / DOI:
doi:10.3390/nu16030373
Publisher:
MDPI AG
E-ISSN:
2072-6643
Date of publication:
26.01.2024
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