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Titel:

Everolimus-eluting stents stabilize plaque inflammation in vivo: assessment by intravascular fluorescence molecular imaging.

Dokumenttyp:
Journal Article; Journal Article
Autor(en):
Calfon Press, Marcella A; Mallas, Georgios; Rosenthal, Amir; Hara, Tetsuya; Mauskapf, Adam; Nudelman, R Nika; Sheehy, Alexander; Polyakov, Igor V; Kolodgie, Frank; Virmani, Renu; Guerrero, J Luis; Ntziachristos, Vasilis; Jaffer, Farouc A
Abstract:
Inflammation drives atherosclerosis complications and is a promising therapeutic target for plaque stabilization. At present, it is unknown whether local stenting approaches can stabilize plaque inflammation in vivo. Here, we investigate whether everolimus-eluting stents (EES) can locally suppress plaque inflammatory protease activity in vivo using intravascular near-infrared fluorescence (NIRF) molecular imaging.Balloon-injured, hyperlipidaemic rabbits with atherosclerosis received non-overlapp...     »
Zeitschriftentitel:
Eur Heart J Cardiovasc Imaging
Jahr:
2017
Band / Volume:
18
Heft / Issue:
5
Seitenangaben Beitrag:
510-518
Sprache:
eng
Volltext / DOI:
doi:10.1093/ehjci/jew228
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28039209
Print-ISSN:
2047-2404
TUM Einrichtung:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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