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Titel:

Mouse redox histology using genetically encoded probes.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Fujikawa, Yuuta; Roma, Leticia P; Sobotta, Mirko C; Rose, Adam J; Diaz, Mauricio Berriel; Locatelli, Giuseppe; Breckwoldt, Michael O; Misgeld, Thomas; Kerschensteiner, Martin; Herzig, Stephan; Müller-Decker, Karin; Dick, Tobias P
Abstract:
Mapping the in vivo distribution of endogenous oxidants in animal tissues is of substantial biomedical interest. Numerous health-related factors, including diet, physical activity, infection, aging, toxins, or pharmacological intervention, may cause redox changes. Tools are needed to pinpoint redox state changes to particular organs, tissues, cell types, and subcellular organelles. We describe a procedure that preserves the in vivo redox state of genetically encoded redox biosensors within histo...     »
Zeitschriftentitel:
Sci Signal
Jahr:
2016
Band / Volume:
9
Heft / Issue:
419
Seitenangaben Beitrag:
rs1
Sprache:
eng
Volltext / DOI:
doi:10.1126/scisignal.aad3895
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26980443
Print-ISSN:
1945-0877
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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