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Title:

Towards Understanding Male Infertility After Spinal Cord Injury Using Quantitative Proteomics

Document type:
Zeitschriftenaufsatz
Author(s):
da Silva, Barbara Ferreira; Meng, Chen; Helm, Dominic; Pachl, Fiona; Schiller, Jürgen; Ibrahim, Emad; Lynne, Charles M.; Brackett, Nancy L.; Bertolla, Ricardo Pimenta; Kuster, Bernhard
Abstract:
The study of male infertility after spinal cord injury (SCI) has enhanced the understanding of seminal plasma (SP) as an important regulator of spermatozoa function. However, the most important factors leading to the diminished sperm motility and viability observed in semen of men with SCI remained unknown. Thus, to explore SP related molecular mechanisms underlying infertility after SCI, we used mass spectrometry-based quantitative proteomics to compare SP retrieved from SCI patients to normal...     »
Keywords:
BayBioMS
Journal title:
Molecular & Cellular Proteomics
Year:
2016
Journal volume:
15
Journal issue:
4
Pages contribution:
1424-1434
Fulltext / DOI:
doi:10.1074/mcp.m115.052175
Publisher:
American Society for Biochemistry & Molecular Biology (ASBMB)
E-ISSN:
1535-94761535-9484
Date of publication:
26.01.2016
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