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Title:

Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues.

Document type:
Journal Article; Article
Author(s):
Tzoumas, Stratis; Nunes, Antonio; Olefir, Ivan; Stangl, Stefan; Symvoulidis, Panagiotis; Glasl, Sarah; Bayer, Christine; Multhoff, Gabriele; Ntziachristos, Vasilis
Abstract:
Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption has limited the quantification accuracy of optical and optoacoustic spectroscopic methods, and impeded the goal of imaging blood oxygen saturation (sO2) deep in tissues; a critical goal for the assessment of oxygenation in physiological processes and disease. Here we describe light fluence in the spectral domain...     »
Journal title abbreviation:
Nat Commun
Year:
2016
Journal volume:
7
Pages contribution:
12121
Language:
eng
Fulltext / DOI:
doi:10.1038/ncomms12121
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27358000
Print-ISSN:
2041-1723
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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