This thesis highlights the potential of endolysin in combination with high hydrostatic pressure to eradicate Gram-positive pathogens in foods. This work demonstrates that endolysins can substantially enhance the bactericidal effect of high pressure and enable the inactivation of cells at milder pressure parameters. New insights into the mechanistic background of bacterial inactivation by the combination of these techniques are provided, the understanding of endolysin’s antimicrobial activity is deepened, and the role of the cell wall in high pressure resistance is highlighted.
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This thesis highlights the potential of endolysin in combination with high hydrostatic pressure to eradicate Gram-positive pathogens in foods. This work demonstrates that endolysins can substantially enhance the bactericidal effect of high pressure and enable the inactivation of cells at milder pressure parameters. New insights into the mechanistic background of bacterial inactivation by the combination of these techniques are provided, the understanding of endolysin’s antimicrobial activity is...
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