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Title:

Spatial constraints dictate glial territories at murine neuromuscular junctions.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Brill, Monika S; Lichtman, Jeff W; Thompson, Wesley; Zuo, Yi; Misgeld, Thomas
Abstract:
Schwann cells (SCs), the glial cells of the peripheral nervous system, cover synaptic terminals, allowing them to monitor and modulate neurotransmission. Disruption of glial coverage leads to axon degeneration and synapse loss. The cellular mechanisms that establish and maintain this coverage remain largely unknown. To address this, we labeled single SCs and performed time-lapse imaging experiments. Adult terminal SCs are arranged in static tile patterns, whereas young SCs dynamically intermingl...     »
Journal title abbreviation:
J Cell Biol
Year:
2011
Journal volume:
195
Journal issue:
2
Pages contribution:
293-305
Language:
eng
Fulltext / DOI:
doi:10.1083/jcb.201108005
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22006952
Print-ISSN:
0021-9525
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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