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Titel:

Spatial constraints dictate glial territories at murine neuromuscular junctions.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Autor(en):
Brill, Monika S; Lichtman, Jeff W; Thompson, Wesley; Zuo, Yi; Misgeld, Thomas
Abstract:
Schwann cells (SCs), the glial cells of the peripheral nervous system, cover synaptic terminals, allowing them to monitor and modulate neurotransmission. Disruption of glial coverage leads to axon degeneration and synapse loss. The cellular mechanisms that establish and maintain this coverage remain largely unknown. To address this, we labeled single SCs and performed time-lapse imaging experiments. Adult terminal SCs are arranged in static tile patterns, whereas young SCs dynamically intermingl...     »
Zeitschriftentitel:
J Cell Biol
Jahr:
2011
Band / Volume:
195
Heft / Issue:
2
Seitenangaben Beitrag:
293-305
Sprache:
eng
Volltext / DOI:
doi:10.1083/jcb.201108005
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22006952
Print-ISSN:
0021-9525
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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