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Titel:

Voltage-dependent inwardly rectifying potassium conductance in the outer membrane of neuronal mitochondria.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Autor(en):
Fieni, Francesca; Parkar, Anjum; Misgeld, Thomas; Kerschensteiner, Martin; Lichtman, Jeff W; Pasinelli, Piera; Trotti, Davide
Abstract:
Potassium fluxes integrate mitochondria into cellular activities, controlling their volume homeostasis and structural integrity in many pathophysiological mechanisms. The outer mitochondrial membrane (OMM) is thought to play a passive role in this process because K(+) is believed to equilibrate freely between the cytosol and mitochondrial intermembrane space. By patch clamping mitochondria isolated from the central nervous systems of adult mitoCFP transgenic mice, we discovered the existence of...     »
Zeitschriftentitel:
J Biol Chem
Jahr:
2010
Band / Volume:
285
Heft / Issue:
35
Seitenangaben Beitrag:
27411-7
Sprache:
eng
Volltext / DOI:
doi:10.1074/jbc.M110.131243
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20551319
Print-ISSN:
0021-9258
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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