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Titel:

Anti-IL-4 as a new strategy in allergy.

Dokumenttyp:
Journal Article
Autor(en):
Schmidt-Weber, CB
Abstract:
Allergic diseases are characterized by an overreaction characterized by Th2-type cell response, and as a consequence, an IgE-switched B cell immunity. Obviously, type-2 cytokines (IL-4, IL-5, IL-9, IL-13) and particularly IL-4 have been identified as potential targets for allergy treatment. While initial experiences using anti-IL-4 principles in asthma were rather ambiguous, more recent studies using an IL-4 mute in blocking the IL-4 and IL-13 receptor have shown promising results. Furthermore,...     »
Zeitschriftentitel:
Chem Immunol Allergy
Jahr:
2012
Band / Volume:
96
Seitenangaben Beitrag:
120-5
Sprache:
eng
Volltext / DOI:
doi:10.1159/000332235
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22433381
Print-ISSN:
1660-2242
TUM Einrichtung:
Molekulare Allergologie (Prof. Schmidt-Weber)
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