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Title:

Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents.

Document type:
Journal Article
Author(s):
Vorberg, I; Raines, A; Story, B; Priola, SA
Abstract:
The risk of contamination of tissue culture cells with transmissible spongiform encephalopathy (TSE) agents as a result of the use of animal products as medium components has been considered to be low, in part, because only a few brain-derived cell lines have been reported to be susceptible to TSE infection. In the present study, we demonstrate that the common laboratory fibroblast cell lines NIH/3T3 and L929, which express low levels of cellular mouse prion protein, are susceptible to infection...     »
Journal title abbreviation:
J Infect Dis
Year:
2004
Journal volume:
189
Journal issue:
3
Pages contribution:
431-9
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14745700
Print-ISSN:
0022-1899
TUM Institution:
Institut für Virologie
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