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Titel:

Gating of the expressed T-type Cav3.1 calcium channels is modulated by Ca2+.

Dokumenttyp:
Journal Article; Article
Autor(en):
Lacinova, L; Kurejova, M; Klugbauer, N; Hofmann, F
Abstract:
AIM: We have investigated the influence of Ca2+ ions on the basic biophysical properties of T-type calcium channels. METHODS: The Cav3.1 calcium channel was transiently expressed in HEK 293 cells. Current was measured using the whole cell patch clamp technique. Ca2+ or Na+ ions were used as charge carriers. The intracellular Ca2+ was either decreased by the addition of 10 mm ethyleneglycoltetraacetic acid (EGTA) or increased by the addition of 200 microm Ca2+ into the non-buffered intracellular...     »
Zeitschriftentitel:
Acta Physiol (Oxf)
Jahr:
2006
Band / Volume:
186
Heft / Issue:
4
Seitenangaben Beitrag:
249-60
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1748-1716.2006.01539.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16634780
Print-ISSN:
1748-1708
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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