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Titel:

Abnormal neocortical development in mice lacking cGMP-dependent protein kinase I.

Dokumenttyp:
Journal Article; Article
Autor(en):
Demyanenko, GP; Halberstadt, AI; Pryzwansky, KB; Werner, C; Hofmann, F; Maness, PF
Abstract:
Cyclic GMP-dependent protein kinase type I (cGKI) is a key signaling intermediate important for synaptic potentiation in the hippocampus and cerebellum, but its expression and function in cortical development have not been elucidated. The expression of cGKI in the developing mouse neocortex was evaluated by immunofluorescence labeling, and effect of cGKI deletion on cortical development was studied in adult cGKI knockout mice. cGKI was expressed at highest levels at embryonic stages in young neu...     »
Zeitschriftentitel:
Brain Res Dev Brain Res
Jahr:
2005
Band / Volume:
160
Heft / Issue:
1
Seitenangaben Beitrag:
1-8
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.devbrainres.2005.07.013
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16154207
Print-ISSN:
0165-3806
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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