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Titel:

Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guérin by Flt3-ligand generated dendritic cells.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
von Meyenn, F; Schaefer, M; Weighardt, H; Bauer, S; Kirschning, CJ; Wagner, H; Sparwasser, T
Abstract:
Recognition of mycobacteria by the innate immune system is essential for the development of an adaptive immune response. Mycobacterial antigens stimulate antigen presenting cells (APCs) through distinct Toll-like receptors (TLRs) resulting in rapid activation of the innate immune system. The role of TLRs during infection with Mycobacterium bovis Bacillus Calmette-Guérin (BCG) has been evaluated for TLR2 and TLR4 only. Surprisingly, despite the fact that immune stimulatory CpG-motifs have been or...     »
Zeitschriftentitel:
Immunobiology
Jahr:
2006
Band / Volume:
211
Heft / Issue:
6-8
Seitenangaben Beitrag:
557-65
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.imbio.2006.05.004
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16920494
Print-ISSN:
0171-2985
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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