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Title:

An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.

Document type:
Clinical Trial; Clinical Trial, Phase II; Journal Article; Article
Author(s):
Reichardt, P; Oechsle, K; Pink, D; Bokemeyer, C; Schneller, F; Issels, R; Kanz, L; Hartmann, JT
Abstract:
BACKGROUND: The number of effective cytotoxic agents for the treatment of patients with metastatic soft tissue sarcoma (STS) is limited, especially when patients have failed anthracyline-based chemotherapy. PATIENTS AND METHODS: Between 1999 and 2000 a total of 16 patients with histologically proven STS progressing during or after first-line anthracycline-based chemotherapy were entered into this open-label, noncomparative study. Topotecan was administered as a 30-min infusion at a dosage of 1.5...     »
Journal title abbreviation:
Invest New Drugs
Year:
2003
Journal volume:
21
Journal issue:
4
Pages contribution:
481-6
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14586217
Print-ISSN:
0167-6997
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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