User: Guest  Login
Less Searchfields
Simple search
Title:

IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice.

Document type:
Journal Article
Author(s):
Bronte, V; Serafini, P; De Santo, C; Marigo, I; Tosello, V; Mazzoni, A; Segal, DM; Staib, C; Löwel, M; Sutter, G; Colombo, MP; Zanovello, P
Abstract:
We previously demonstrated that a specialized subset of immature myeloid cells migrate to lymphoid organs as a result of tumor growth or immune stress, where they suppress B and T cell responses to Ags. Although NO was required for suppression of mitogen activation of T cells by myeloid suppressor cells (MSC), it was not required for suppression of allogenic responses. In this study, we describe a novel mechanism used by MSC to block T cell proliferation and CTL generation in response to alloant...     »
Journal title abbreviation:
J Immunol
Year:
2003
Journal volume:
170
Journal issue:
1
Pages contribution:
270-8
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12496409
Print-ISSN:
0022-1767
TUM Institution:
Institut für Virologie
 BibTeX