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Title:

Characterization of all human male synaptonemal complexes by subtelomere multiplex-FISH.

Document type:
Journal Article; Article
Author(s):
Codina-Pascual, M; Kraus, J; Speicher, MR; Oliver-Bonet, M; Murcia, V; Sarquella, J; Egozcue, J; Navarro, J; Benet, J
Abstract:
During meiotic prophase I, homologous chromosomes synapse and recombine. Both events are of vital importance for the success of meiosis. When homologous chromosomes synapse, a proteinaceous structure called synaptonemal complex (SC) appears along the pairing axis and meiotic recombination takes place. The existence of immunolabeling techniques for SC proteins (SCP1, SCP2 and SCP3) and for DNA mismatch repair proteins present in late recombination nodules (MLH1) allow analyses of both synapsis an...     »
Journal title abbreviation:
Cytogenet Genome Res
Year:
2004
Journal volume:
107
Journal issue:
1-2
Pages contribution:
18-21
Language:
eng
Fulltext / DOI:
doi:10.1159/000079566
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15305051
Print-ISSN:
1424-8581
TUM Institution:
Institut für Humangenetik
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