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Title:

Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium.

Document type:
Journal Article
Author(s):
Marcus, DC; Liu, J; Lee, JH; Scherer, EQ; Scofield, MA; Wangemann, P
Abstract:
BACKGROUND: It was previously shown that K+ secretion by strial marginal cell epithelium is under the control of G-protein coupled receptors of the P2Y family in the apical membrane. Receptor activation by uracil nucleotides (P2Y2, P2Y4 or P2Y6) leads to a decrease in the electrogenic K+ secretion. The present study was conducted to determine the subtype of the functional purinergic receptor in gerbil stria vascularis, to test if receptor activation leads to elevation of intracellular [Ca2+] and...     »
Journal title abbreviation:
Cell Commun Signal
Year:
2005
Journal volume:
3
Pages contribution:
13
Language:
eng
Fulltext / DOI:
doi:10.1186/1478-811X-3-13
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16266433
Print-ISSN:
1478-811X
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik
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