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Title:

Thienopyridines and other ADP-receptor antagonists.

Document type:
Journal Article; Review
Author(s):
Bernlochner, I; Sibbing, D
Abstract:
Platelet P2Y12 receptor inhibition plays a pivotal role in preventing thrombotic vascular events in patients with ACS and in patients undergoing percutaneous coronary intervention (PCI). Among the P2Y12 receptor inhibitors, the group of thienopyridines include ticlopidine, clopidogrel and prasugrel, all of which are orally administered prodrugs leading to irreversible P2Y12 receptor inhibition. Non-thienopyridine derivatives including ticagrelor, cangrelor and elinogrel do not require metabolic...     »
Journal title abbreviation:
Handb Exp Pharmacol
Year:
2012
Journal issue:
210
Pages contribution:
165-98
Language:
eng
Fulltext / DOI:
doi:10.1007/978-3-642-29423-5_7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22918731
Print-ISSN:
0171-2004
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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