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Document type:
Journal Article; Article
Author(s):
Luther, T; Kotzsch, M; Meye, A; Langerholc, T; Fussel, S; Olbricht, N; Albrecht, S; Ockert, D; Muehlenweg, B; Friedrich, K; Grosser, M; Schmitt, M; Baretton, G; Magdolen, V
Title:
Identification of a novel urokinase receptor splice variant and its prognostic relevance in breast cancer.
Abstract:
The cellular receptor for urokinase-type plasminogen activator, uPAR, plays a central role in both cell surface-associated proteolysis and cellular adhesion. In the present study, we systematically searched for splice variants of uPAR mRNA in human cells and tumor tissues by qualitative RT-PCR using specific primers for uPAR exons 1 and 6. Beside the wild-type (wt) uPAR mRNA and the previously described splice variant lacking exon 5 (uPAR-del5), a novel splice variant lacking both exons 4 and 5...     »
Journal title abbreviation:
Thromb Haemost
Year:
2003
Journal volume:
89
Journal issue:
4
Pages contribution:
705-17
Language:
eng
Fulltext / DOI:
doi:10.1267/THRO03040705
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12669126
Print-ISSN:
0340-6245
TUM Institution:
Frauenklinik und Poliklinik
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