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Title:

Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients.

Document type:
Clinical Trial; Journal Article; Article
Author(s):
Beer, AJ; Haubner, R; Goebel, M; Luderschmidt, S; Spilker, ME; Wester, HJ; Weber, WA; Schwaiger, M
Abstract:
(18)F-Galacto-RGD has been developed for PET of alpha(v)beta(3) integrin expression, a receptor involved in, for example, angiogenesis and metastasis. Our aim was to study the kinetics and biodistribution of (18)F-Galacto-RGD in cancer patients. METHODS: Nineteen patients with metastases of malignant melanoma (n = 7), sarcomas (n = 10), or osseous metastases (n = 2) were examined. After injection of 133-200 MBq (18)F-Galacto-RGD, 3 consecutive emission scans from the pelvis to the thorax or dyna...     »
Journal title abbreviation:
J Nucl Med
Year:
2005
Journal volume:
46
Journal issue:
8
Pages contribution:
1333-41
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16085591
Print-ISSN:
0161-5505
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Orthopädie und Sportorthopädie
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