User: Guest  Login
Less Searchfields
Simple search
Title:

Inactivation of the viral interleukin 1beta receptor improves CD8+ T-cell memory responses elicited upon immunization with modified vaccinia virus Ankara.

Document type:
Journal Article
Author(s):
Staib, C; Kisling, S; Erfle, V; Sutter, G
Abstract:
Interleukin 1 (IL1) is an important regulator of inflammatory responses and contributes to host immune defence against infection. Vaccinia virus encodes a viral soluble IL1beta receptor (IL1betaR), which modulates the acute-phase host response to infection and might influence the induction of immune responses against virus-associated antigens. Here, modified vaccinia virus Ankara (MVA) mutants defective in IL1betaR production were produced by insertion of selectable marker gene sequences that pr...     »
Journal title abbreviation:
J Gen Virol
Year:
2005
Journal volume:
86
Journal issue:
Pt 7
Pages contribution:
1997-2006
Language:
eng
Fulltext / DOI:
doi:10.1099/vir.0.80646-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15958679
Print-ISSN:
0022-1317
TUM Institution:
Institut für Virologie
 BibTeX