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Titel:

Voltage-dependent effects of barnidipine in rat vascular smooth muscle.

Dokumenttyp:
Journal Article; Article
Autor(en):
Wegener, JW; Korstanje, C; Nawrath, H
Abstract:
The effects of the dihydropyridine nifedipine and its more lipophilic congener, barnidipine, were investigated in smooth muscle preparations from the rat in resting and depolarizing conditions. Both drugs relaxed precontracted aortic rings more potently in depolarizing conditions, barnidipine being more potent than nifedipine. Currents through Ca2+ channels in rat vascular smooth muscle cells (A7r5) and in isolated rat cardiomyocytes were reduced more potently by both drugs at a holding potentia...     »
Zeitschriftentitel:
J Cardiovasc Pharmacol
Jahr:
2003
Band / Volume:
42
Heft / Issue:
2
Seitenangaben Beitrag:
218-23
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12883325
Print-ISSN:
0160-2446
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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