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Title:

Voltage-dependent effects of barnidipine in rat vascular smooth muscle.

Document type:
Journal Article; Article
Author(s):
Wegener, JW; Korstanje, C; Nawrath, H
Abstract:
The effects of the dihydropyridine nifedipine and its more lipophilic congener, barnidipine, were investigated in smooth muscle preparations from the rat in resting and depolarizing conditions. Both drugs relaxed precontracted aortic rings more potently in depolarizing conditions, barnidipine being more potent than nifedipine. Currents through Ca2+ channels in rat vascular smooth muscle cells (A7r5) and in isolated rat cardiomyocytes were reduced more potently by both drugs at a holding potentia...     »
Journal title abbreviation:
J Cardiovasc Pharmacol
Year:
2003
Journal volume:
42
Journal issue:
2
Pages contribution:
218-23
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12883325
Print-ISSN:
0160-2446
TUM Institution:
Institut für Pharmakologie und Toxikologie
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