Benutzer: Gast  Login
Weniger Felder
Einfache Suche
Titel:

Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice.

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Feil, R; Lohmann, SM; de Jonge, H; Walter, U; Hofmann, F
Abstract:
Signaling cascades initiated by nitric oxide (NO) and natriuretic peptides (NPs) play an important role in the maintenance of cardiovascular homeostasis. It is currently accepted that many effects of these endogenous signaling molecules are mediated via stimulation of guanylyl cyclases and intracellular production of the second messenger cGMP. Indeed, cGMP-elevating drugs like glyceryl trinitrate have been used for more than 100 years to treat cardiovascular diseases. However, the molecular mech...     »
Zeitschriftentitel:
Circ Res
Jahr:
2003
Band / Volume:
93
Heft / Issue:
10
Seitenangaben Beitrag:
907-16
Sprache:
eng
Volltext / DOI:
doi:10.1161/01.RES.0000100390.68771.CC
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/14615494
Print-ISSN:
0009-7330
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
 BibTeX