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Titel:

cGMP-dependent protein kinase II modulates mPer1 and mPer2 gene induction and influences phase shifts of the circadian clock.

Dokumenttyp:
Journal Article; Article
Autor(en):
Oster, H; Werner, C; Magnone, MC; Mayser, H; Feil, R; Seeliger, MW; Hofmann, F; Albrecht, U
Abstract:
BACKGROUND: In mammals, the master circadian clock that drives many biochemical, physiological, and behavioral rhythms is located in the suprachiasmatic nuclei (SCN) of the hypothalamus. Generation and maintenance of circadian rhythmicity rely on complex interlocked transcriptional/translational feedback loops involving a set of clock genes. Among the molecular components driving the mammalian circadian clock are the Period 1 and 2 (mPer1 and mPer2) genes. Because the periodicity of the clock is...     »
Zeitschriftentitel:
Curr Biol
Jahr:
2003
Band / Volume:
13
Heft / Issue:
9
Seitenangaben Beitrag:
725-33
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12725729
Print-ISSN:
0960-9822
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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