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Dokumenttyp:
Journal Article; Article
Autor(en):
Mempel, M; Ronet, C; Lemaître, F; Lim, A; Kourilsky, P; Gachelin, G; Musette, P
Titel:
The intratumoral application of poly-G-oligodeoxynucleotides does not augment the naturally induced antitumoral CD8-T-cell response in P815 mastocytomas.
Abstract:
DNA sequences containing CpG have been described to induce a strong immune reaction by acting on a variety of immune cells including a strong and pronounced antitumoral response. Poly-G-oligodeoxynucleotides (ODNs) on the other hand have been attributed the preferential induction of CD8-T-cell proliferation when used in vitro. This activity led us to the investigation of the possible antitumoral properties of poly-G-ODNs in an established CD8-dependent tumor eradication model. We used the well d...     »
Zeitschriftentitel:
Immunol Lett
Jahr:
2003
Band / Volume:
89
Heft / Issue:
1
Seitenangaben Beitrag:
47-57
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12946864
Print-ISSN:
0165-2478
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie
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