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Title:

The interleukin-13 production by peripheral blood T cells from atopic dermatitis patients does not require CD2 costimulation.

Document type:
Journal Article; Article
Author(s):
Simon, D; Von Gunten, S; Borelli, S; Braathen, LR; Simon, HU
Abstract:
BACKGROUND: Although allergic mechanisms appear to be important, the pathogenesis of both extrinsic and intrinsic forms of atopic dermatitis (AD) is unknown. METHODS: We compared the cytokine production of peripheral blood mononuclear cells of extrinsic AD (EAD) and intrinsic AD (IAD) patients and normal control individuals after stimulation with anti-CD3 and/or anti-CD28 monoclonal antibodies (mAbs) in the presence or absence of anti-CD2-blocking mAb. The cytokine production was measured by imm...     »
Journal title abbreviation:
Int Arch Allergy Immunol
Year:
2003
Journal volume:
132
Journal issue:
2
Pages contribution:
148-55
Language:
eng
Fulltext / DOI:
doi:10.1159/000073716
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14600427
Print-ISSN:
1018-2438
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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