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Title:

Human scleroderma sera contain autoantibodies to protein components specific to the U3 small nucleolar RNP complex.

Document type:
Journal Article; Article
Author(s):
Yang, JM; Hildebrandt, B; Luderschmidt, C; Pollard, KM
Abstract:
OBJECTIVE: To determine whether antifibrillarin autoantibodies in scleroderma patients are associated with autoantibodies to protein components specific for U3 small nucleolar RNP (U3 snoRNP). METHODS: Sera from 220 scleroderma patients were examined for antinucleolar autoantibodies (ANoA) and for antibodies to fibrillarin and the U3 snoRNP-specific proteins Mpp10 and hU3-55K. Clinical correlates were determined for the different autoantibody specificities. RESULTS: Fifty-nine of the 220 patient...     »
Journal title abbreviation:
Arthritis Rheum
Year:
2003
Journal volume:
48
Journal issue:
1
Pages contribution:
210-7
Language:
eng
Fulltext / DOI:
doi:10.1002/art.10729
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12528121
Print-ISSN:
0004-3591
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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