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Title:

Laboratory acquired infection with recombinant vaccinia virus containing an immunomodulating construct.

Document type:
Case Reports; Journal Article; Article
Author(s):
Mempel, M; Isa, G; Klugbauer, N; Meyer, H; Wildi, G; Ring, J; Hofmann, F; Hofmann, H
Abstract:
Handling of Vaccinia virus represents a risk for laboratory-acquired infections, especially in individuals without completed vaccination. We report the case of a Vaccinia infection in a previously vaccinated researcher working with various genetically modified strains. We could confirm the infection by electron microscopy, positive cell culture, virus-specific PCR, sequence analysis, and viral neutralization test. The isolated virus carried a functionally inactivated cytohesin-1 gene of human or...     »
Journal title abbreviation:
J Invest Dermatol
Year:
2003
Journal volume:
120
Journal issue:
3
Pages contribution:
356-8
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12603846
Print-ISSN:
0022-202X
TUM Institution:
Institut für Pharmakologie und Toxikologie; Klinik und Poliklinik für Dermatologie und Allergologie
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