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Titel:

Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Keller, C; Hoffmann, R; Lang, R; Brandau, S; Hermann, C; Ehlers, S
Abstract:
Classical twin studies and recent linkage analyses of African populations have revealed a potential involvement of host genetic factors in susceptibility or resistance to Mycobacterium tuberculosis infection. In order to identify the candidate genes involved and test their causal implication, we capitalized on the mouse model of tuberculosis, since inbred mouse strains also differ substantially in their susceptibility to infection. Two susceptible and two resistant mouse strains were aerogenical...     »
Zeitschriftentitel:
Infect Immun
Jahr:
2006
Band / Volume:
74
Heft / Issue:
7
Seitenangaben Beitrag:
4295-309
Sprache:
eng
Volltext / DOI:
doi:10.1128/IAI.00057-06
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16790804
Print-ISSN:
0019-9567
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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